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Def1 Promotes the Degradation of Pol3 for Polymerase Exchange to Occur During DNA-Damage–Induced Mutagenesis in Saccharomyces cerevisiae

DNA damages hinder the advance of replication forks because of the inability of the replicative polymerases to synthesize across most DNA lesions. Because stalled replication forks are prone to undergo DNA breakage and recombination that can lead to chromosomal rearrangements and cell death, cells p...

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Detalles Bibliográficos
Autores principales:	Daraba, Andreea, Gali, Vamsi K., Halmai, Miklós, Haracska, Lajos, Unk, Ildiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897375/ https://www.ncbi.nlm.nih.gov/pubmed/24465179 http://dx.doi.org/10.1371/journal.pbio.1001771

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