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Surfactant Secretion in LRRK2 Knock-Out Rats: Changes in Lamellar Body Morphology and Rate of Exocytosis
Leucine-rich repeat kinase 2 (LRRK2) is known to play a role in the pathogenesis of various diseases including Parkinson disease, morbus Crohn, leprosy and cancer. LRRK2 is suggested to be involved in a number of cell biological processes such as vesicular trafficking, transcription, autophagy and l...
Autores principales: | Miklavc, Pika, Ehinger, Konstantin, Thompson, Kristin E., Hobi, Nina, Shimshek, Derya R., Frick, Manfred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897396/ https://www.ncbi.nlm.nih.gov/pubmed/24465451 http://dx.doi.org/10.1371/journal.pone.0084926 |
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