Generation of “Virtual” Control Groups for Single Arm Prostate Cancer Adjuvant Trials

It is difficult to construct a control group for trials of adjuvant therapy (Rx) of prostate cancer after radical prostatectomy (RP) due to ethical issues and patient acceptance. We utilized 8 curve-fitting models to estimate the time to 60%, 65%, … 95% chance of progression free survival (PFS) base...

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Detalles Bibliográficos
Autores principales: Jia, Zhenyu, Lilly, Michael B., Koziol, James A., Chen, Xin, Xia, Xiao-Qin, Wang, Yipeng, Skarecky, Douglas, Sutton, Manuel, Sawyers, Anne, Ruckle, Herbert, Carpenter, Philip M., Wang-Rodriguez, Jessica, Jiang, Jun, Deng, Mingsen, Pan, Cong, Zhu, Jian-guo, McLaren, Christine E., Gurley, Michael J., Lee, Chung, McClelland, Michael, Ahlering, Thomas, Kattan, Michael W., Mercola, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897405/
https://www.ncbi.nlm.nih.gov/pubmed/24465467
http://dx.doi.org/10.1371/journal.pone.0085010

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