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Development of a Highly Sensitive and Specific Method for Detection of Circulating Tumor Cells Harboring Somatic Mutations in Non-Small-Cell Lung Cancer Patients

BACKGROUND: Oncogenic mutations are powerful predictive biomarkers for molecularly targeted cancer therapies. For mutation detection patients have to undergo invasive tumor biopsies. Alternatively, archival samples are used which may no longer reflect the actual tumor status. Circulating tumor cells...

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Detalles Bibliográficos
Autores principales:	Breitenbuecher, Frank, Hoffarth, Sandra, Worm, Karl, Cortes-Incio, Diana, Gauler, Thomas C., Köhler, Jens, Herold, Thomas, Schmid, Kurt Werner, Freitag, Lutz, Kasper, Stefan, Schuler, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897440/ https://www.ncbi.nlm.nih.gov/pubmed/24465542 http://dx.doi.org/10.1371/journal.pone.0085350

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