Mutation Analysis of the ERCC4/FANCQ Gene in Hereditary Breast Cancer

The ERCC4 protein forms a structure-specific endonuclease involved in the DNA damage response. Different cancer syndromes such as a subtype of Xeroderma pigmentosum, XPF, and recently a subtype of Fanconi Anemia, FA-Q, have been attributed to biallelic ERCC4 gene mutations. To investigate whether mo...

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Detalles Bibliográficos
Autores principales: Kohlhase, Sandra, Bogdanova, Natalia V., Schürmann, Peter, Bermisheva, Marina, Khusnutdinova, Elza, Antonenkova, Natalia, Park-Simon, Tjoung-Won, Hillemanns, Peter, Meyer, Andreas, Christiansen, Hans, Schindler, Detlev, Dörk, Thilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897449/
https://www.ncbi.nlm.nih.gov/pubmed/24465539
http://dx.doi.org/10.1371/journal.pone.0085334

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