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Synergistic Anti-Cancer Effect of Phenformin and Oxamate

Phenformin (phenethylbiguanide; an anti-diabetic agent) plus oxamate [lactate dehydrogenase (LDH) inhibitor] was tested as a potential anti-cancer therapeutic combination. In in vitro studies, phenformin was more potent than metformin, another biguanide, recently recognized to have anti-cancer effec...

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Detalles Bibliográficos
Autores principales:	Miskimins, W. Keith, Ahn, Hyun Joo, Kim, Ji Yeon, Ryu, Sun, Jung, Yuh-Seog, Choi, Joon Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897486/ https://www.ncbi.nlm.nih.gov/pubmed/24465604 http://dx.doi.org/10.1371/journal.pone.0085576

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