Cargando…

Identification of Mutations in the PYRIN-Containing NLR Genes (NLRP) in Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma (HNSCC) encompasses malignancies that arise in the mucosa of the upper aerodigestive tract. Recent high throughput DNA sequencing revealed HNSCC genes mutations that contribute to several cancer cell characteristics, including dysregulation of cell proliferation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lei, Yu, Lui, Vivian W. Y., Grandis, Jennifer R., Egloff, Ann Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897487/ https://www.ncbi.nlm.nih.gov/pubmed/24465623 http://dx.doi.org/10.1371/journal.pone.0085619

Ejemplares similares

MAPK1(E322K) mutation increases head and neck squamous cell carcinoma sensitivity to erlotinib through enhanced secretion of amphiregulin
por: Wen, Yihui, et al.
Publicado: (2016)

Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome
por: Shim, Do-Wan, et al.
Publicado: (2018)

Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors
por: Egloff, Ann Marie, et al.
Publicado: (2009)

Challenges in EGFRvIII Detection in Head and Neck Squamous Cell Carcinoma
por: Wheeler, Sarah E., et al.
Publicado: (2015)

Pyrin- and CARD-only Proteins as Regulators of NLR Functions
por: Le, Hongnga T., et al.
Publicado: (2013)

β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows
por: Dong, Zhihao, et al.
Publicado: (2022)

The NLR family pyrin domain containing 3 inflammasome in the mechanism of electroacupuncture: Current status and future perspectives
por: Yuan, Min, et al.
Publicado: (2022)

Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation
por: Zhang, Cong, et al.
Publicado: (2021)

NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study
por: Kunnas, Tarja, et al.
Publicado: (2015)

Structural and Functional Analysis of the NLRP4 Pyrin Domain
por: Eibl, Clarissa, et al.
Publicado: (2012)

Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis
por: Zhang, Haosheng, et al.
Publicado: (2021)

Didymin, a natural flavonoid, relieves the progression of myocardial infarction via inhibiting the NLR family pyrin domain containing 3 inflammasome
por: Zhang, Yong, et al.
Publicado: (2022)

Targeting the NOD-, LRR- and Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome in Psoriasis and Fatigue
por: Seguro, Charmaine Kue, et al.
Publicado: (2022)

The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases
por: de Torre-Minguela, Carlos, et al.
Publicado: (2017)

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
por: Stutz, Andrea, et al.
Publicado: (2017)

Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice
por: Wang, Lei, et al.
Publicado: (2021)

Activation of NLR family, domain of pyrin containing 3 inflammasome by nitrous oxide through thioredoxin-interacting protein to induce nerve cell injury
por: Liu, WenJuan, et al.
Publicado: (2021)

Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells
por: Ge, Yishan, et al.
Publicado: (2021)

Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck Cancer
por: Peyser, Noah D., et al.
Publicado: (2015)

A Novel Mutation in the Pyrin Domain of the NOD-like Receptor Family Pyrin Domain Containing Protein 3 in Muckle-Wells Syndrome
por: Hu, Jian, et al.
Publicado: (2017)

Overexpressed CD39 mitigates sepsis-induced kidney epithelial cell injury via suppressing the activation of NLR family pyrin domain containing 3
por: Yang, Meixia, et al.
Publicado: (2019)

Curcumin relieves paraquat-induced lung injury through inhibiting the thioredoxin interacting protein/NLR pyrin domain containing 3-mediated inflammatory pathway
por: Ren, Yi, et al.
Publicado: (2019)

Triptolide improves myocardial fibrosis in rats through inhibition of nuclear factor kappa B and NLR family pyrin domain containing 3 inflammasome pathway
por: Shen, Jianyao, et al.
Publicado: (2021)

Herpes Simplex Virus 1 Induces Microglia Gasdermin D-Dependent Pyroptosis Through Activating the NLR Family Pyrin Domain Containing 3 Inflammasome
por: Hu, Xiao, et al.
Publicado: (2022)

Knocking down ETS Proto-oncogene 1 (ETS1) alleviates the pyroptosis of renal tubular epithelial cells in patients with acute kidney injury by regulating the NLR family pyrin domain containing 3 (NLRP3) transcription
por: Juan, Chenxia, et al.
Publicado: (2022)

APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma
por: Cannataro, Vincent L., et al.
Publicado: (2019)

Pyrin
Publicado: (1860)

Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy
por: Xu, Jia, et al.
Publicado: (2022)

AA amyloidosis and pyrin gene mutations
por: Konstantopoulos, K., et al.
Publicado: (2005)

Analysis of oncogenic activities of protein kinase D1 in head and neck squamous cell carcinoma
por: Zhang, Liyong, et al.
Publicado: (2018)

An informatics supported web-based data annotation and query tool to expedite translational research for head and neck malignancies
por: Amin, Waqas, et al.
Publicado: (2009)

Collagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion
por: Sok, J C, et al.
Publicado: (2013)

Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5′-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice
por: Jin, Lei, et al.
Publicado: (2022)

JAK Kinase Inhibition Abrogates STAT3 Activation and Head and Neck Squamous Cell Carcinoma Tumor Growth()()
por: Sen, Malabika, et al.
Publicado: (2015)

Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer
por: Peyser, Noah D., et al.
Publicado: (2016)

Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss
por: Gross, Andrew M, et al.
Publicado: (2014)

FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway
por: Wei, Jianqiang, et al.
Publicado: (2023)

Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage
por: Ren, Honglei, et al.
Publicado: (2018)

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome
por: Yang, Xuejun, et al.
Publicado: (2018)

4373 Defining the role of non-canonical PIK3CA mutations in head and neck squamous cell carcinoma
por: Lee, Michelle Ji-Eun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f3cee1lchj91lg79he0dnpcdh5