Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?

Accumulating evidence suggests that high-endothelial venules (HEVs) represent major gateways for the infiltration of lymphocytes within neoplastic lesions. However, the origin of these vessels in human neoplasms remains elusive. We have recently discovered a link between lymphotoxin β-producing dend...

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Detalles Bibliográficos
Autores principales: Martinet, Ludovic, Girard, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897501/
https://www.ncbi.nlm.nih.gov/pubmed/24482745
http://dx.doi.org/10.4161/onci.26470
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author Martinet, Ludovic
Girard, Jean-Philippe
author_facet Martinet, Ludovic
Girard, Jean-Philippe
author_sort Martinet, Ludovic
collection PubMed
description Accumulating evidence suggests that high-endothelial venules (HEVs) represent major gateways for the infiltration of lymphocytes within neoplastic lesions. However, the origin of these vessels in human neoplasms remains elusive. We have recently discovered a link between lymphotoxin β-producing dendritic cells and tumor-associated HEVs.
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spelling pubmed-38975012014-01-30 Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer? Martinet, Ludovic Girard, Jean-Philippe Oncoimmunology Author's View Accumulating evidence suggests that high-endothelial venules (HEVs) represent major gateways for the infiltration of lymphocytes within neoplastic lesions. However, the origin of these vessels in human neoplasms remains elusive. We have recently discovered a link between lymphotoxin β-producing dendritic cells and tumor-associated HEVs. Landes Bioscience 2013-11-01 2013-10-10 /pmc/articles/PMC3897501/ /pubmed/24482745 http://dx.doi.org/10.4161/onci.26470 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Martinet, Ludovic
Girard, Jean-Philippe
Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title_full Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title_fullStr Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title_full_unstemmed Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title_short Regulation of tumor-associated high-endothelial venules by dendritic cells: A new opportunity to promote lymphocyte infiltration into breast cancer?
title_sort regulation of tumor-associated high-endothelial venules by dendritic cells: a new opportunity to promote lymphocyte infiltration into breast cancer?
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897501/
https://www.ncbi.nlm.nih.gov/pubmed/24482745
http://dx.doi.org/10.4161/onci.26470
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AT girardjeanphilippe regulationoftumorassociatedhighendothelialvenulesbydendriticcellsanewopportunitytopromotelymphocyteinfiltrationintobreastcancer

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