A Lifespan Observation of a Novel Mouse Model: In Vivo Evidence Supports Aβ Oligomer Hypothesis

Transgenic mouse models are powerful tools in exploring the mechanisms of AD. Most current transgenic models of AD mimic the memory impairment and the main pathologic features, among which the formation of beta-amyloid (Aβ) plaques is considered a dominant pathologic event. Recently, Aβ oligomers ha...

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Detalles Bibliográficos
Autores principales: Zhang, Yichi, Lu, Lu, Jia, Jianping, Jia, Longfei, Geula, Changiz, Pei, Jinjing, Xu, Zhiqing, Qin, Wei, Liu, Ruiqin, Li, Dan, Pan, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897547/
https://www.ncbi.nlm.nih.gov/pubmed/24465766
http://dx.doi.org/10.1371/journal.pone.0085885

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