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Improved Anchorage of Ti6Al4V Orthopaedic Bone Implants through Oligonucleotide Mediated Immobilization of BMP-2 in Osteoporotic Rats

The aim of the present study was to test the biocompatibility and functionality of orthopaedic bone implants with immobilized oligonucleotides serving as anchor stands for rhBMP-2 and rhVEGF-A conjugated with complementary oligonucleotides in an osteoporotic rat model. Al(2)O(3)-blasted acid etched...

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Detalles Bibliográficos
Autores principales:	Wölfle, Julia V., Fiedler, Jörg, Dürselen, Lutz, Reichert, Judith, Scharnweber, Dieter, Förster, Anne, Schwenzer, Bernd, Reichel, Heiko, Ignatius, Anita, Brenner, Rolf E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897651/ https://www.ncbi.nlm.nih.gov/pubmed/24465929 http://dx.doi.org/10.1371/journal.pone.0086151

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