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SHP-1 Arrests Mouse Early Embryo Development through Downregulation of Nanog by Dephosphorylation of STAT3

Src-homology protein tyrosine phosphatase-1 (SHP-1) is a protein tyrosine phosphatase that is implicated in the regulation of growth, differentiation, survival, apoptosis and proliferation of hematopoietic cells and other cell types. Here, we found that SHP-1 is involved in regulation of early embry...

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Detalles Bibliográficos
Autores principales: Yin, Songna, Wu, Haibo, Lv, Jiaxing, Wu, Xinying, Zhang, Yan, Du, Juan, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897670/
https://www.ncbi.nlm.nih.gov/pubmed/24466030
http://dx.doi.org/10.1371/journal.pone.0086330