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Aggregation of Human Recombinant Monoclonal Antibodies Influences the Capacity of Dendritic Cells to Stimulate Adaptive T-Cell Responses In Vitro

Subvisible proteinaceous particles which are present in all therapeutic protein formulations are in the focus of intense discussions between health authorities, academics and biopharmaceutical companies in the context of concerns that such particles could promote unwanted immunogenicity via anti-dru...

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Detalles Bibliográficos
Autores principales:	Rombach-Riegraf, Verena, Karle, Anette C., Wolf, Babette, Sordé, Laetitia, Koepke, Stephan, Gottlieb, Sascha, Krieg, Jennifer, Djidja, Marie-Claude, Baban, Aida, Spindeldreher, Sebastian, Koulov, Atanas V., Kiessling, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897673/ https://www.ncbi.nlm.nih.gov/pubmed/24466023 http://dx.doi.org/10.1371/journal.pone.0086322

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