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Perturbation of Human Coronary Artery Endothelial Cell Redox State and NADPH Generation by Methylglyoxal
Diabetes is associated with elevated plasma glucose, increased reactive aldehyde formation, oxidative damage, and glycation/glycoxidation of biomolecules. Cellular detoxification of, or protection against, such modifications commonly requires NADPH-dependent reducing equivalents (e.g. GSH). We hypot...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897751/ https://www.ncbi.nlm.nih.gov/pubmed/24466151 http://dx.doi.org/10.1371/journal.pone.0086564 |