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Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report

Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only after two failed adequate antipsychotics trials. We report a cas...

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Detalles Bibliográficos
Autores principales: Kim, Yeon-Jin, No, Seung-Ho, Lee, Sang-Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897767/
https://www.ncbi.nlm.nih.gov/pubmed/24465255
http://dx.doi.org/10.9758/cpn.2013.11.3.168
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author Kim, Yeon-Jin
No, Seung-Ho
Lee, Sang-Yeol
author_facet Kim, Yeon-Jin
No, Seung-Ho
Lee, Sang-Yeol
author_sort Kim, Yeon-Jin
collection PubMed
description Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only after two failed adequate antipsychotics trials. We report a case of a successful early clozapine trial in the treatment of first-episode schizophrenia patient, considering poor treatment response and repeated self-injurious behavior. This case highlights the efficacy of an early clozapine trial as a second-line treatment for first-episode schizophrenia in contrast to switching or combination treatment strategy.
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spelling pubmed-38977672014-01-24 Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report Kim, Yeon-Jin No, Seung-Ho Lee, Sang-Yeol Clin Psychopharmacol Neurosci Case Report Clozapine remains the treatment of choice in refractory schizophrenia despite its various requirement to prescribe, such as mandatory blood monitoring program and various metabolic complication. Currently, clozapine is recommended only after two failed adequate antipsychotics trials. We report a case of a successful early clozapine trial in the treatment of first-episode schizophrenia patient, considering poor treatment response and repeated self-injurious behavior. This case highlights the efficacy of an early clozapine trial as a second-line treatment for first-episode schizophrenia in contrast to switching or combination treatment strategy. Korean College of Neuropsychopharmacology 2013-12 2013-12-24 /pmc/articles/PMC3897767/ /pubmed/24465255 http://dx.doi.org/10.9758/cpn.2013.11.3.168 Text en Copyright© 2013, Korean College of Neuropsychopharmacology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Yeon-Jin
No, Seung-Ho
Lee, Sang-Yeol
Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title_full Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title_fullStr Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title_full_unstemmed Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title_short Successful Early Clozapine Trial in the Treatment of First-episode Schizophrenia: A Case Report
title_sort successful early clozapine trial in the treatment of first-episode schizophrenia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897767/
https://www.ncbi.nlm.nih.gov/pubmed/24465255
http://dx.doi.org/10.9758/cpn.2013.11.3.168
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