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The costimulatory molecule B7-H4 promote tumor progression and cell proliferation through translocating into nucleus

B7-H4, a member of B7 family, is a transmembrane protein and inhibits T-cells immunity. However, in a variety of tumor cells, B7-H4 was detected predominantly in intracellular compartments with unknown mechanism and functions. In this study, we analyzed B7-H4 expression and subcellular distribution...

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Detalles Bibliográficos
Autores principales: Zhang, L, Wu, H, Lu, D, Li, G, Sun, C, Song, H, Li, J, Zhai, T, Huang, Lv, Hou, C, Wang, W, Zhou, B, Chen, S, Lu, B, Zhang, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898118/
https://www.ncbi.nlm.nih.gov/pubmed/23318460
http://dx.doi.org/10.1038/onc.2012.600