Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex

The majority of the polytopic proteins that are synthesized at the ER (endoplasmic reticulum) are integrated co-translationally via the Sec61 translocon, which provides lateral access for their hydrophobic TMs (transmembrane regions) to the phospholipid bilayer. A prolonged association between TMs o...

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Detalles Bibliográficos
Autores principales: Watson, Helen R., Wunderley, Lydia, Andreou, Tereza, Warwicker, Jim, High, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898203/
https://www.ncbi.nlm.nih.gov/pubmed/24015703
http://dx.doi.org/10.1042/BJ20130100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898203/
https://www.ncbi.nlm.nih.gov/pubmed/24015703
http://dx.doi.org/10.1042/BJ20130100

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