Cargando…
Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex
The majority of the polytopic proteins that are synthesized at the ER (endoplasmic reticulum) are integrated co-translationally via the Sec61 translocon, which provides lateral access for their hydrophobic TMs (transmembrane regions) to the phospholipid bilayer. A prolonged association between TMs o...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898203/ https://www.ncbi.nlm.nih.gov/pubmed/24015703 http://dx.doi.org/10.1042/BJ20130100 |