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Genomic instability in pre-neoplastic colonic lesions

Genomic instability is a characteristic of most cancers and it is argued that genomic instability is a driving force for tumorigenesis. Data herein demonstrate that genomic instability, as evidenced by microsatellite instability (MSI) and promoter methylation of DNA mismatch repair genes, is common...

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Detalles Bibliográficos
Autores principales:	Shaw, J A, Graham, T A, Stebbing, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898279/ https://www.ncbi.nlm.nih.gov/pubmed/23396367 http://dx.doi.org/10.1038/onc.2013.21

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