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Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate Helicobacter felis-induced gastric carcinogenesis in C57BL/6 mice

The classical nuclear factor-kappaB (NF-κB) signaling pathway has been shown to be important in a number of models of inflammation-associated cancer. In a mouse model of Helicobacter-induced gastric cancer, impairment of classical NF-κB signaling in the gastric epithelium led to the development of i...

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Detalles Bibliográficos
Autores principales: Burkitt, M D, Williams, J M, Duckworth, C A, O'Hara, A, Hanedi, A, Varro, A, Caamaño, J H, Pritchard, D M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898319/
https://www.ncbi.nlm.nih.gov/pubmed/23975431
http://dx.doi.org/10.1038/onc.2013.334