Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth

Endothelial cells express S100A4, a metastasis-associated protein, but its role in angiogenesis remains to be elucidated. Here we show that knockdown of S100A4 in mouse endothelial MSS31 cells by murine specific small interference RNA (mS100A4 siRNA) markedly suppressed capillary-like tube formation...

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Detalles Bibliográficos
Autores principales: Ochiya, Takahiro, Takenaga, Keizo, Endo, Hideya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898373/
https://www.ncbi.nlm.nih.gov/pubmed/23929008
http://dx.doi.org/10.1007/s10456-013-9372-7

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