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Shear-induced endothelial mechanotransduction: the interplay between reactive oxygen species (ROS) and nitric oxide (NO) and the pathophysiological implications

Hemodynamic shear stress, the blood flow-generated frictional force acting on the vascular endothelial cells, is essential for endothelial homeostasis under normal physiological conditions. Mechanosensors on endothelial cells detect shear stress and transduce it into biochemical signals to trigger v...

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Detalles Bibliográficos
Autores principales:	Hsieh, Hsyue-Jen, Liu, Ching-Ann, Huang, Bin, Tseng, Anne HH, Wang, Danny Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898375/ https://www.ncbi.nlm.nih.gov/pubmed/24410814 http://dx.doi.org/10.1186/1423-0127-21-3

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