Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII

Ionizing radiation (IR) is an integral part of modern multimodal anti-cancer therapies. IR involves the formation of reactive oxygen species (ROS) in targeted tissues. This is associated with subsequent cardiac dysfunction when applied during chest radiotherapy. We hypothesized that IR (i.e., ROS)-d...

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Detalles Bibliográficos
Autores principales: Sag, Can M., Wolff, Hendrik A., Neumann, Kay, Opiela, Marie-Kristin, Zhang, Juqian, Steuer, Felicia, Sowa, Thomas, Gupta, Shamindra, Schirmer, Markus, Hünlich, Mark, Rave-Fränk, Margret, Hess, Clemens F., Anderson, Mark E., Shah, Ajay M., Christiansen, Hans, Maier, Lars S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898380/
https://www.ncbi.nlm.nih.gov/pubmed/24068185
http://dx.doi.org/10.1007/s00395-013-0385-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898380/
https://www.ncbi.nlm.nih.gov/pubmed/24068185
http://dx.doi.org/10.1007/s00395-013-0385-6

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