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SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism

An intricate network regulates the activities of SIRT1 and PARP1 proteins and continues to be uncovered. Both SIRT1 and PARP1 share a common co-factor nicotinamide adenine dinucleotide (NAD+) and several common substrates, including regulators of DNA damage response and circadian rhythms. We review...

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Detalles Bibliográficos
Autores principales:	Luna, Augustin, Aladjem, Mirit I, Kohn, Kurt W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898398/ https://www.ncbi.nlm.nih.gov/pubmed/24360018 http://dx.doi.org/10.1186/2041-9414-4-6

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