A peptide derived from TIMP-3 inhibits multiple angiogenic growth factor receptors and tumour growth and inflammatory arthritis in mice

The binding of vascular endothelial growth factor (VEGF) to VEGF receptor-2 (VEGFR-2) on the surface of vascular endothelial cells stimulates many steps in the angiogenic pathway. Inhibition of this interaction is proving of value in moderating the neovascularization accompanying age-related macular...

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Detalles Bibliográficos
Autores principales: Chen, Yung-Yi, Brown, Nicola J., Jones, Rita, Lewis, Claire E., Mujamammi, Ahmed H., Muthana, Munitta, Seed, Michael P., Barker, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898417/
https://www.ncbi.nlm.nih.gov/pubmed/24129822
http://dx.doi.org/10.1007/s10456-013-9389-y

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