Par-4/THAP1 complex and Notch3 competitively regulated pre-mRNA splicing of CCAR1 and affected inversely the survival of T-cell acute lymphoblastic leukemia cells

Although the intensification of therapy for children with T-cell acute lymphoblastic leukemia (T-ALL) has substantially improved clinical outcomes, T-ALL remains an important challenge in pediatric oncology. Here, we report that the cooperative synergy between prostate apoptosis response factor-4 (P...

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Detalles Bibliográficos
Autores principales: Lu, C, Li, J-Y, Ge, Z, Zhang, L, Zhou, G-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898485/
https://www.ncbi.nlm.nih.gov/pubmed/23975424
http://dx.doi.org/10.1038/onc.2013.349

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