Evidence that PICALM affects age at onset of Alzheimer's dementia in Down syndrome

It is known that individuals with Down syndrome develop Alzheimer’s disease with an early age at onset, although associated genetic risk factors have not been widely studied. We tested whether genes that increase the risk of late-onset Alzheimer’s disease influence the age at onset in Down syndrome...

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Detalles Bibliográficos
Autores principales: Jones, Emma L., Mok, Kin, Hanney, Marisa, Harold, Denise, Sims, Rebecca, Williams, Julie, Ballard, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Genetic Reports Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898582/
https://www.ncbi.nlm.nih.gov/pubmed/23601808
http://dx.doi.org/10.1016/j.neurobiolaging.2013.03.018

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