Cargando…
Synergy between Multiple Microtubule-Generating Pathways Confers Robustness to Centrosome-Driven Mitotic Spindle Formation
The mitotic spindle is defined by its organized, bipolar mass of microtubules, which drive chromosome alignment and segregation. Although different cells have been shown to use different molecular pathways to generate the microtubules required for spindle formation, how these pathways are coordinate...
Autores principales: | Hayward, Daniel, Metz, Jeremy, Pellacani, Claudia, Wakefield, James G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898610/ https://www.ncbi.nlm.nih.gov/pubmed/24389063 http://dx.doi.org/10.1016/j.devcel.2013.12.001 |
Ejemplares similares
-
SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression
por: Yuki, Ryuzaburo, et al.
Publicado: (2023) -
Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression
por: Plessner, Matthias, et al.
Publicado: (2019) -
Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis
por: Rasamizafy, Sylvia Fenosoa, et al.
Publicado: (2021) -
Sinup is essential for the integrity of centrosomes and mitotic spindles in zebrafish embryos
por: Yoo, Kyeong-Won, et al.
Publicado: (2017) -
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
por: Goshima, Gohta, et al.
Publicado: (2008)