Spindle Formation in the Mouse Embryo Requires Plk4 in the Absence of Centrioles

During the first five rounds of cell division in the mouse embryo, spindles assemble in the absence of centrioles. Spindle formation initiates around chromosomes, but the microtubule nucleating process remains unclear. Here we demonstrate that Plk4, a protein kinase known as a master regulator of ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Coelho, Paula A., Bury, Leah, Sharif, Bedra, Riparbelli, Maria G., Fu, Jingyan, Callaini, Giuliano, Glover, David M., Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898710/
https://www.ncbi.nlm.nih.gov/pubmed/24268700
http://dx.doi.org/10.1016/j.devcel.2013.09.029

Ejemplares similares

Ejemplares similares