STMN-1 is a potential marker of lymph node metastasis in distal esophageal adenocarcinomas and silencing its expression can reverse malignant phenotype of tumor cells

BACKGROUND: Distal esophageal adenocarcinoma is a highly aggressive neoplasm. Despite advances in diagnosis and therapy, the prognosis is still poor. Stathmin (STMN-1) is a ubiquitously expressed microtubule destabilizing phosphoprotein. It promotes the disassembly of microtubules and prevents assem...

Descripción completa

Detalles Bibliográficos
Autores principales: Akhtar, Javed, Wang, Zhou, Yu, Che, Li, Chen-Sheng, Shi, Yu-Long, Liu, Hong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898730/
https://www.ncbi.nlm.nih.gov/pubmed/24433541
http://dx.doi.org/10.1186/1471-2407-14-28

Ejemplares similares

Ejemplares similares