The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy

Autophagy is an evolutionarily conserved process that enables catabolic and degradative pathways. These pathways commonly depend on vesicular transport controlled by Rabs, small GTPases inactivated by TBC/RabGAPs. The Rac1 effector TBC/RabGAP Armus (TBC1D2A) is known to inhibit Rab7, a key regulator...

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Detalles Bibliográficos
Autores principales: Carroll, Bernadette, Mohd-Naim, Noor, Maximiano, Filipe, Frasa, Marieke A., McCormack, Jessica, Finelli, Mattea, Thoresen, Sigrid B., Perdios, Louis, Daigaku, Reiko, Francis, Richard E., Futter, Clare, Dikic, Ivan, Braga, Vania M.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898768/
https://www.ncbi.nlm.nih.gov/pubmed/23562278
http://dx.doi.org/10.1016/j.devcel.2013.03.005

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