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STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits

Clinically, HER2 proto-oncogene amplification is found in about 25–30% of human breast cancers, where it is correlated to a poor prognosis. Constitutive STAT3 activation is found in about 50–60% of the breast tumors and associated with tumorigenesis and drug resistance. In this study, we showed that...

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Detalles Bibliográficos
Autores principales:	CHUNG, SEYUNG S., GIEHL, NOLAN, WU, YANYUAN, VADGAMA, JAYDUTT V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898805/ https://www.ncbi.nlm.nih.gov/pubmed/24297508 http://dx.doi.org/10.3892/ijo.2013.2195

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