Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication

BACKGROUND: We previously demonstrated that primary Th1Th17 cells are highly permissive to HIV-1, whereas Th1 cells are relatively resistant. Molecular mechanisms underlying these differences remain unknown. RESULTS: Exposure to replication competent and single-round VSV-G pseudotyped HIV strains pr...

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Detalles Bibliográficos
Autores principales: Bernier, Annie, Cleret-Buhot, Aurélie, Zhang, Yuwei, Goulet, Jean-Philippe, Monteiro, Patricia, Gosselin, Annie, DaFonseca, Sandrina, Wacleche, Vanessa Sue, Jenabian, Mohammad-Ali, Routy, Jean-Pierre, Tremblay, Cécile, Ancuta, Petronela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898812/
https://www.ncbi.nlm.nih.gov/pubmed/24359430
http://dx.doi.org/10.1186/1742-4690-10-160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898812/
https://www.ncbi.nlm.nih.gov/pubmed/24359430
http://dx.doi.org/10.1186/1742-4690-10-160

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