Cargando…

PPL2 Translesion Polymerase Is Essential for the Completion of Chromosomal DNA Replication in the African Trypanosome

Faithful copying of the genome is essential for life. In eukaryotes, a single archaeo-eukaryotic primase (AEP), DNA primase, is required for the initiation and progression of DNA replication. Here we have identified additional eukaryotic AEP-like proteins with DNA-dependent primase and/or polymerase...

Descripción completa

Detalles Bibliográficos
Autores principales: Rudd, Sean G., Glover, Lucy, Jozwiakowski, Stanislaw K., Horn, David, Doherty, Aidan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898837/
https://www.ncbi.nlm.nih.gov/pubmed/24267450
http://dx.doi.org/10.1016/j.molcel.2013.10.034