The Four Canonical TPR Subunits of Human APC/C Form Related Homo-Dimeric Structures and Stack in Parallel to Form a TPR Suprahelix()

The anaphase-promoting complex or cyclosome (APC/C) is a large E3 RING-cullin ubiquitin ligase composed of between 14 and 15 individual proteins. A striking feature of the APC/C is that only four proteins are involved in directly recognizing target proteins and catalyzing the assembly of a polyubiqu...

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Detalles Bibliográficos
Autores principales: Zhang, Ziguo, Chang, Leifu, Yang, Jing, Conin, Nora, Kulkarni, Kiran, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898896/
https://www.ncbi.nlm.nih.gov/pubmed/23583778
http://dx.doi.org/10.1016/j.jmb.2013.04.004

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