Cargando…

Prediction of the Number of Activated Genes in Multiple Independent Cd(+2)- and As(+3)-Induced Malignant Transformations of Human Urothelial Cells (UROtsa)

BACKGROUND: Many toxic environmental agents such as cadmium and arsenic are found to be epidemiologically linked to increasing rates of cancers. In vitro studies show that these toxic agents induced malignant transformation in human cells. It is not clear whether such malignant transformation induce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garrett, Scott H., Somji, Seema, Sens, Donald A., Zhang, Ke K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899011/ https://www.ncbi.nlm.nih.gov/pubmed/24465620 http://dx.doi.org/10.1371/journal.pone.0085614

Ejemplares similares

Transformation of Human Urothelial Cells (UROtsa) by As(3+) and Cd(2+) Induces the Expression of Keratin 6a
por: Somji, Seema, et al.
Publicado: (2008)

The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers
por: Hoggarth, Zachary E., et al.
Publicado: (2018)

Loss of N-Cadherin Expression in Tumor Transplants Produced From As(+3)- and Cd(+2)-Transformed Human Urothelial (UROtsa) Cell Lines
por: Sandquist, Elizabeth J., et al.
Publicado: (2016)

SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As(+3)- and Cd(+2)-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC
por: Slusser-Nore, Andrea, et al.
Publicado: (2016)

Expression of hsp 27, hsp 60, hsc 70, and hsp 70 stress response genes in cultured human urothelial cells (UROtsa) exposed to lethal and sublethal concentrations of sodium arsenite.
por: Rossi, Michael R, et al.
Publicado: (2002)

Activation of PPARγ and inhibition of cell proliferation reduces key proteins associated with the basal subtype of bladder cancer in As(3+)-transformed UROtsa cells
por: Mehus, Aaron A., et al.
Publicado: (2020)

The immortalized UROtsa cell line as a potential cell culture model of human urothelium.
por: Rossi, M R, et al.
Publicado: (2001)

ZIP8 expression in human proximal tubule cells, human urothelial cells transformed by Cd(+2) and As(+3) and in specimens of normal human urothelium and urothelial cancer
por: Ajjimaporn, Amornpan, et al.
Publicado: (2012)

Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd(+2 )or As(+3 )transformed human urothelial cells
por: Somji, Seema, et al.
Publicado: (2011)

Pevonedistat Inhibits SOX2 Expression and Sphere Formation but Also Drives the Induction of Terminal Differentiation Markers and Apoptosis within Arsenite-Transformed Urothelial Cells
por: Mehus, Aaron A., et al.
Publicado: (2023)

Zinc, Zinc Transporters, and Cadmium Cytotoxicity in a Cell Culture Model of Human Urothelium
por: Satarug, Soisungwan, et al.
Publicado: (2021)

Proteasomes Are Critical for Maintenance of CD133+CD24+ Kidney Progenitor Cells
por: Al-Marsoummi, Sarmad, et al.
Publicado: (2023)

The unique C- and N-terminal sequences of Metallothionein isoform 3 mediate growth inhibition and Vectorial active transport in MCF-7 cells
por: Voels, Brent, et al.
Publicado: (2017)

Short and long term gene expression variation and networking in human proximal tubule cells when exposed to cadmium
por: Garrett, Scott H, et al.
Publicado: (2013)

Elevated glucose represses lysosomal and mTOR-related genes in renal epithelial cells composed of progenitor CD133(+) cells
por: Shrestha, Swojani, et al.
Publicado: (2021)

Cadherin Expression, Vectorial Active Transport, and Metallothionein Isoform 3 Mediated EMT/MET Responses in Cultured Primary and Immortalized Human Proximal Tubule Cells
por: Slusser, Andrea, et al.
Publicado: (2015)

Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCl2.
por: Somji, S, et al.
Publicado: (1999)

Expression of the constitutive and inducible forms of heat shock protein 70 in human proximal tubule cells exposed to heat, sodium arsenite, and CdCl(2).
por: Somji, S, et al.
Publicado: (1999)

Exposure of human proximal tubule cells to cd2+, zn2+, and Cu2+ induces metallothionein protein accumulation but not metallothionein isoform 2 mRNA.
por: Garrett, S H, et al.
Publicado: (1998)

STEERing an IDeA in Undergraduate Research at a Rural Research Intensive University
por: Sens, Donald A., et al.
Publicado: (2017)

Meta-analysis of gene expression profiling reveals novel basal gene signatures in MCF-10A cells transformed with cadmium
por: Blommel, Katrina, et al.
Publicado: (2020)

Cross-Contamination of a UROtsa Stock with T24 Cells – Molecular Comparison of Different Cell Lines and Stocks
por: Johnen, Georg, et al.
Publicado: (2013)

Contamination Assessment and Potential Human Health Risks of Heavy Metals in Urban Soils from Grand Forks, North Dakota, USA
por: Saleem, Muhammad, et al.
Publicado: (2023)

Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer
por: Soh, Maureen A, et al.
Publicado: (2011)

Chronic Arsenic Exposure Upregulates the Expression of Basal Transcriptional Factors and Increases Invasiveness of the Non-Muscle Invasive Papillary Bladder Cancer Line RT4
por: Mehus, Aaron A., et al.
Publicado: (2022)

Arsenite Exposure to Human RPCs (HRTPT) Produces a Reversible Epithelial Mesenchymal Transition (EMT): In-Vitro and In-Silico Study
por: Singhal, Sonalika, et al.
Publicado: (2023)

Synchronous Urothelial Carcinoma of the Bladder and Urachal Adenoma with Subsequent Malignant Transformation
por: Pan, David, et al.
Publicado: (2012)

Role of HRTPT in kidney proximal epithelial cell regeneration: Integrative differential expression and pathway analyses using microarray and scRNA‐seq
por: Shrestha, Swojani, et al.
Publicado: (2021)

Differential expression of human metallothionein isoform I mRNA in human proximal tubule cells exposed to metals.
por: Garrett, S H, et al.
Publicado: (1998)

Protein interactions with metallothionein-3 promote vectorial active transport in human proximal tubular cells
por: Kalyan, Gazal, et al.
Publicado: (2022)

Predictive Markers for Malignant Urothelial Transformation in Balkan Endemic Nephropathy: A Case–Control Study
por: Kocic, Gordana, et al.
Publicado: (2020)

Metallothionein isoform 3 as a potential biomarker for human bladder cancer.
por: Sens, M A, et al.
Publicado: (2000)

Primary and Immortalized Cultures of Human Proximal Tubule Cells Possess Both Progenitor and Non-Progenitor Cells That Can Impact Experimental Results
por: Shrestha, Swojani, et al.
Publicado: (2023)

A Rare Urothelial Malignant Transformation in a Mature Cystic Teratoma of the Ovary
por: Iijima, Moito, et al.
Publicado: (2021)

Multiple primary malignancies: synchronous urothelial carcinoma of the bladder and adenocarcinoma of the colon
por: Queiroz, Rodolfo Mendes, et al.
Publicado: (2017)

Multiple Familial Trichoepithelioma with Malignant Transformation
por: Samaka, Rehab M, et al.
Publicado: (2013)

DPP4/CD26 overexpression in urothelial carcinoma confers an independent prognostic impact and correlates with intrinsic biological aggressiveness
por: Liang, Peir-In, et al.
Publicado: (2016)

Cadmium, Environmental Exposure, and Health Outcomes
por: Satarug, Soisungwan, et al.
Publicado: (2010)

Ovarian endometriosis: risk factor analysis and prediction of malignant transformation
por: Zhou, YanNa, et al.
Publicado: (2018)

Concurrent Preoperative Presence of Hydronephrosis and Flank Pain Independently Predicts Worse Outcome of Upper Tract Urothelial Carcinoma
por: Yeh, Hsin-Chih, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_uamqu6pme5l0tc5fs9rpt1jfdq