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Complement therapy in atypical haemolytic uraemic syndrome (aHUS)
Central to the pathogenesis of atypical haemolytic uraemic syndrome (aHUS) is over-activation of the alternative pathway of complement. Inherited defects in complement genes and autoantibodies against complement regulatory proteins have been described. The use of plasma exchange to replace non-funct...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pergamon Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899040/ https://www.ncbi.nlm.nih.gov/pubmed/23810412 http://dx.doi.org/10.1016/j.molimm.2013.05.224 |