Complement therapy in atypical haemolytic uraemic syndrome (aHUS)

Central to the pathogenesis of atypical haemolytic uraemic syndrome (aHUS) is over-activation of the alternative pathway of complement. Inherited defects in complement genes and autoantibodies against complement regulatory proteins have been described. The use of plasma exchange to replace non-funct...

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Detalles Bibliográficos
Autores principales: Wong, Edwin K.S., Goodship, Tim H.J., Kavanagh, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899040/
https://www.ncbi.nlm.nih.gov/pubmed/23810412
http://dx.doi.org/10.1016/j.molimm.2013.05.224

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