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On the Value of Intra-Motif Dependencies of Human Insulator Protein CTCF
The binding affinity of DNA-binding proteins such as transcription factors is mainly determined by the base composition of the corresponding binding site on the DNA strand. Most proteins do not bind only a single sequence, but rather a set of sequences, which may be modeled by a sequence motif. Algo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899044/ https://www.ncbi.nlm.nih.gov/pubmed/24465627 http://dx.doi.org/10.1371/journal.pone.0085629 |