A Functional Genetic Variant (N521D) in Natriuretic Peptide Receptor 3 Is Associated with Diastolic Dysfunction: The Prevalence of Asymptomatic Ventricular Dysfunction Study

OBJECTIVES: To evaluate the impact of a functional genetic variant in the natriuretic peptide clearance receptor, NPR3, on circulating natriuretic peptides (NPs) and myocardial structure and function in the general community. BACKGROUND: NPR3 plays an important role in the clearance of NPs and throu...

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Detalles Bibliográficos
Autores principales: Pereira, Naveen L., Redfield, Margaret M., Scott, Christopher, Tosakulwong, Nirubol, Olson, Timothy M., Bailey, Kent R., Rodeheffer, Richard J., Burnett, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899045/
https://www.ncbi.nlm.nih.gov/pubmed/24465655
http://dx.doi.org/10.1371/journal.pone.0085708

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