Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells

miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma therapy, we conducted genome-wide target mapping i...

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Detalles Bibliográficos
Autores principales: Tamim, Saleh, Vo, Dat T., Uren, Philip J., Qiao, Mei, Bindewald, Eckart, Kasprzak, Wojciech K., Shapiro, Bruce A., Nakaya, Helder I., Burns, Suzanne C., Araujo, Patricia R., Nakano, Ichiro, Radek, Agnes J., Kuersten, Scott, Smith, Andrew D., Penalva, Luiz O. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899048/
https://www.ncbi.nlm.nih.gov/pubmed/24465609
http://dx.doi.org/10.1371/journal.pone.0085591

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