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Smoking Modifies the Associated Increased Risk of Future Cardiovascular Disease by Genetic Variation on Chromosome 9p21

AIMS: Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors. METHODS AND RESULTS: A to...

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Detalles Bibliográficos
Autores principales: Hamrefors, Viktor, Hedblad, Bo, Hindy, George, Smith, J. Gustav, Almgren, Peter, Engström, Gunnar, Sjögren, Marketa, Gränsbo, Klas, Orho-Melander, Marju, Melander, Olle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899088/
https://www.ncbi.nlm.nih.gov/pubmed/24465769
http://dx.doi.org/10.1371/journal.pone.0085893