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The statistical-mechanics of chromosome conformation capture

Since Jacob and Monod’s characterization of the role of DNA elements in gene control, it has been recognized that the linear organization of genome structure is important for the regulation of gene transcription and hence the manifestation of phenotypes. Similarly, it has long been hypothesized that...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Justin M, Hendy, Michael D, Pichugina, Tatyana, Wake, Graeme C, Langowski, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899129/
https://www.ncbi.nlm.nih.gov/pubmed/24051548
http://dx.doi.org/10.4161/nucl.26513