Comparison of HDAC inhibitors in clinical development: Effect on HIV production in latently infected cells and T-cell activation

Objective: We aimed to compare the potential for inducing HIV production and the effect on T-cell activation of potent HDAC inhibitors undergoing clinical investigation. Design: In vitro study Methods: The latently infected cell lines ACH2 and U1 were treated with the HDAC inhibitors panobinostat, g...

Descripción completa

Detalles Bibliográficos
Autores principales: Rasmussen, Thomas Aagaard, Søgaard, Ole Schmeltz, Brinkmann, Christel, Wightman, Fiona, Lewin, Sharon R., Melchjorsen, Jesper, Dinarello, Charles, Østergaard, Lars, Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899169/
https://www.ncbi.nlm.nih.gov/pubmed/23370291
http://dx.doi.org/10.4161/hv.23800

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899169/
https://www.ncbi.nlm.nih.gov/pubmed/23370291
http://dx.doi.org/10.4161/hv.23800

Ejemplares similares