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HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China

OBJECTIVES: Acceptability of pre-exposure prophylaxis (PrEP) and willingness to participate in a clinical trial for both safety and efficacy of PrEP were investigated among female sex workers (FSWs) in Guangxi, China. METHODS: A cross-sectional study was performed in three cities in Guangxi. Structu...

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Autores principales: Ye, Li, Wei, Suosu, Zou, Yunfeng, Yang, Xiaobo, Abdullah, Abu S., Zhong, Xiaoni, Ruan, Yuhua, Lin, Xinqin, Li, Mingqiang, Wu, Deren, Jiang, Junjun, Xie, Peiyan, Huang, Jiegang, Liang, Bingyu, Zhou, Bo, Su, Jinming, Liang, Hao, Huang, Ailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899205/
https://www.ncbi.nlm.nih.gov/pubmed/24465956
http://dx.doi.org/10.1371/journal.pone.0086200
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author Ye, Li
Wei, Suosu
Zou, Yunfeng
Yang, Xiaobo
Abdullah, Abu S.
Zhong, Xiaoni
Ruan, Yuhua
Lin, Xinqin
Li, Mingqiang
Wu, Deren
Jiang, Junjun
Xie, Peiyan
Huang, Jiegang
Liang, Bingyu
Zhou, Bo
Su, Jinming
Liang, Hao
Huang, Ailong
author_facet Ye, Li
Wei, Suosu
Zou, Yunfeng
Yang, Xiaobo
Abdullah, Abu S.
Zhong, Xiaoni
Ruan, Yuhua
Lin, Xinqin
Li, Mingqiang
Wu, Deren
Jiang, Junjun
Xie, Peiyan
Huang, Jiegang
Liang, Bingyu
Zhou, Bo
Su, Jinming
Liang, Hao
Huang, Ailong
author_sort Ye, Li
collection PubMed
description OBJECTIVES: Acceptability of pre-exposure prophylaxis (PrEP) and willingness to participate in a clinical trial for both safety and efficacy of PrEP were investigated among female sex workers (FSWs) in Guangxi, China. METHODS: A cross-sectional study was performed in three cities in Guangxi. Structured, self-administered questionnaires were used to assess the acceptability of PrEP and the willingness to participate in a clinical trial. Multivariable logistic regression models were fitted to identify predictors. RESULTS: Among 405 participants, 15.1% had heard of PrEP. If PrEP was deemed to be effective, safe and provided for free, 85.9% reported that they would accept it, and 54.3% of those who accepted PrEP said that they would participate in a clinical trial. The increased acceptability of PrEP was associated with working in male dominated venues, higher income, a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, not being forced to use condoms by the gatekeepers, consistent use of condoms, and use of drugs to prevent STD infection. The increased willingness to participate in a clinical trial was associated with a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, a willingness to adhere to daily PreP use, and not being concerned about discrimination by others. The main reason for rejecting PrEP or participating in a clinical trial was the concern about the side effects of PrEP. CONCLUSIONS: Acceptability of PrEP among Guangxi FSWs is relatively high, indicating that PrEP intervention programs may be feasible for Chinese FSWs. Given the fact that most of the participants had never heard of PrEP before, and that family, gatekeepers, and social discrimination could significantly affect its acceptability, a comprehensive mix of multiple interventions is necessary for the successful implementation of a PrEP program among this population in Guangxi.
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spelling pubmed-38992052014-01-24 HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China Ye, Li Wei, Suosu Zou, Yunfeng Yang, Xiaobo Abdullah, Abu S. Zhong, Xiaoni Ruan, Yuhua Lin, Xinqin Li, Mingqiang Wu, Deren Jiang, Junjun Xie, Peiyan Huang, Jiegang Liang, Bingyu Zhou, Bo Su, Jinming Liang, Hao Huang, Ailong PLoS One Research Article OBJECTIVES: Acceptability of pre-exposure prophylaxis (PrEP) and willingness to participate in a clinical trial for both safety and efficacy of PrEP were investigated among female sex workers (FSWs) in Guangxi, China. METHODS: A cross-sectional study was performed in three cities in Guangxi. Structured, self-administered questionnaires were used to assess the acceptability of PrEP and the willingness to participate in a clinical trial. Multivariable logistic regression models were fitted to identify predictors. RESULTS: Among 405 participants, 15.1% had heard of PrEP. If PrEP was deemed to be effective, safe and provided for free, 85.9% reported that they would accept it, and 54.3% of those who accepted PrEP said that they would participate in a clinical trial. The increased acceptability of PrEP was associated with working in male dominated venues, higher income, a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, not being forced to use condoms by the gatekeepers, consistent use of condoms, and use of drugs to prevent STD infection. The increased willingness to participate in a clinical trial was associated with a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, a willingness to adhere to daily PreP use, and not being concerned about discrimination by others. The main reason for rejecting PrEP or participating in a clinical trial was the concern about the side effects of PrEP. CONCLUSIONS: Acceptability of PrEP among Guangxi FSWs is relatively high, indicating that PrEP intervention programs may be feasible for Chinese FSWs. Given the fact that most of the participants had never heard of PrEP before, and that family, gatekeepers, and social discrimination could significantly affect its acceptability, a comprehensive mix of multiple interventions is necessary for the successful implementation of a PrEP program among this population in Guangxi. Public Library of Science 2014-01-22 /pmc/articles/PMC3899205/ /pubmed/24465956 http://dx.doi.org/10.1371/journal.pone.0086200 Text en © 2014 Ye et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ye, Li
Wei, Suosu
Zou, Yunfeng
Yang, Xiaobo
Abdullah, Abu S.
Zhong, Xiaoni
Ruan, Yuhua
Lin, Xinqin
Li, Mingqiang
Wu, Deren
Jiang, Junjun
Xie, Peiyan
Huang, Jiegang
Liang, Bingyu
Zhou, Bo
Su, Jinming
Liang, Hao
Huang, Ailong
HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title_full HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title_fullStr HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title_full_unstemmed HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title_short HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China
title_sort hiv pre-exposure prophylaxis interest among female sex workers in guangxi, china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899205/
https://www.ncbi.nlm.nih.gov/pubmed/24465956
http://dx.doi.org/10.1371/journal.pone.0086200
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