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Protein Kinase C Phosphomimetics Alter Thin Filament Ca(2+) Binding Properties

Adrenergic stimulation modulates cardiac function by altering the phosphorylation status of several cardiac proteins. The Troponin complex, which is the Ca(2+) sensor for cardiac contraction, is a hot spot for adrenergic phosphorylation. While the effect of β-adrenergic related PKA phosphorylation o...

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Detalles Bibliográficos
Autores principales:	Liu, Bin, Lopez, Joseph J., Biesiadecki, Brandon J., Davis, Jonathan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899258/ https://www.ncbi.nlm.nih.gov/pubmed/24466001 http://dx.doi.org/10.1371/journal.pone.0086279

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