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Toll-Like Receptor 9 Signaling Delays Neutrophil Apoptosis by Increasing Transcription of Mcl-1

Neutrophils detect bacterial constituents, including bacterial DNA (CpG DNA), which elicits innate immunity and prolongs the functional life span of neutrophils through suppression of apoptosis. Both the anti-apoptotic protein Mcl-1 and activation of NF-κB have been implicated in neutrophil survival...

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Detalles Bibliográficos
Autores principales:	El Kebir, Driss, Damlaj, Anas, Filep, János G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899359/ https://www.ncbi.nlm.nih.gov/pubmed/24466313 http://dx.doi.org/10.1371/journal.pone.0087006

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