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TRAIL/DR5 Signaling Promotes Macrophage Foam Cell Formation by Modulating Scavenger Receptor Expression

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) has been shown to have protective effects against atherosclerosis. However, whether TRAIL has any effects on expression of macrophage scavenger receptors and lipid uptake has not yet been studied. Macrophage lines RAW264.7 and THP...

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Detalles Bibliográficos
Autores principales: Liu, Fang Fang, Wu, Xiao, Zhang, Yun, Wang, Yan, Jiang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899365/
https://www.ncbi.nlm.nih.gov/pubmed/24466325
http://dx.doi.org/10.1371/journal.pone.0087059