Cargando…

Sirtuin 1 (SIRT1) Activation Mediates Sildenafil Induced Delayed Cardioprotection against Ischemia-Reperfusion Injury in Mice

BACKGROUND: It has been well documented that phosphodiesterase-5 inhibitor, sildenafil (SIL) protects against myocardial ischemia/reperfusion (I-R) injury. SIRT1 is part of the class III Sirtuin family of histone deacetylases that deacetylates proteins involved in cellular stress response including...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shalwala, Mona, Zhu, Shu-Guang, Das, Anindita, Salloum, Fadi N., Xi, Lei, Kukreja, Rakesh C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899366/ https://www.ncbi.nlm.nih.gov/pubmed/24466304 http://dx.doi.org/10.1371/journal.pone.0086977

Ejemplares similares

Preclinical model of type 1 diabetes and myocardial ischemia/reperfusion injury in conscious rabbits—demonstration of cardioprotection with rapamycin
por: Samidurai, Arun, et al.
Publicado: (2021)

Anti-Inflammatory and Cardioprotective Effects of Tadalafil in Diabetic Mice
por: Varma, Amit, et al.
Publicado: (2012)

Reperfusion Therapy with Rapamycin Attenuates Myocardial Infarction through Activation of AKT and ERK
por: Filippone, Scott M., et al.
Publicado: (2017)

Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1
por: Zhang, Ji, et al.
Publicado: (2021)

Sildenafil (Viagra) sensitizes prostate cancer cells to doxorubicin-mediated apoptosis through CD95
por: Das, Anindita, et al.
Publicado: (2015)

Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury
por: Madhani, Melanie, et al.
Publicado: (2010)

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury
por: Prag, Hiran A., et al.
Publicado: (2022)

Phosphodiesterase-5 inhibition and cardioprotection: potential role of hydrogen sulfide
por: Kukreja, Rakesh C, et al.
Publicado: (2009)

The Role of Sirtuin 1 (SIRT1) in Neurodegeneration
por: Razick, Daniel I, et al.
Publicado: (2023)

Cardioprotective effects of empagliflozin after ischemia and reperfusion in rats
por: Seefeldt, Jacob Marthinsen, et al.
Publicado: (2021)

Cardioprotective Effect of Cilostazol on Ischemia-Reperfusion Injury Model
por: Sahin, Mazlum, et al.
Publicado: (2022)

Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles
por: Lee, Byung Rho, et al.
Publicado: (2019)

SIRT1/SIRT3 Modulates Redox Homeostasis during Ischemia/Reperfusion in the Aging Heart
por: Zhang, Jingwen, et al.
Publicado: (2020)

Cardioprotective Effects of Quercetin in Cardiomyocyte under Ischemia/Reperfusion Injury
por: Chen, Yi-Wen, et al.
Publicado: (2013)

Cardioprotective Properties of Omecamtiv Mecarbil against Ischemia and Reperfusion Injury
por: Stroethoff, Martin, et al.
Publicado: (2019)

Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection
por: Vörös, Imre, et al.
Publicado: (2021)

EFFECT OF L-VALINE TREATMENT ON SIRTUIN (SIRT1 AND SIRT2) ISOFORMS
por: Sharma, Shakshi, et al.
Publicado: (2022)

Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers
por: Chun, Sung Kook, et al.
Publicado: (2018)

Value of Serum Sirtuin-1 (SIRT1) Levels and SIRT1 Gene Variants in Periodontitis Patients
por: Kriaučiūnas, Albertas, et al.
Publicado: (2022)

Cardioprotective effects of lixisenatide in rat myocardial ischemia-reperfusion injury studies
por: Wohlfart, Paulus, et al.
Publicado: (2013)

Cardioprotective Effect of Betulinic Acid on Myocardial Ischemia Reperfusion Injury in Rats
por: Xia, Anzhou, et al.
Publicado: (2014)

Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts
por: Han, Jichun, et al.
Publicado: (2014)

Cardioprotection provided by Echinatin against ischemia/reperfusion in isolated rat hearts
por: Tian, Xing-han, et al.
Publicado: (2016)

Cardioprotective effects of Achillea wilhelmsii on the isolated rat heart in ischemia–reperfusion
por: Mahmoudabady, M., et al.
Publicado: (2017)

Novel Molecular Targets Participating in Myocardial Ischemia-Reperfusion Injury and Cardioprotection
por: Liu, Nan-Bo, et al.
Publicado: (2019)

Cardioprotective effect of sonic hedgehog ligand in pig models of ischemia reperfusion
por: Ghaleh, Bijan, et al.
Publicado: (2020)

The Role of Sirtuin-1 (SIRT1) in the Physiology and Pathophysiology of the Human Placenta
por: Wątroba, Mateusz, et al.
Publicado: (2023)

Regulation of Sirtuin-Mediated Protein Deacetylation by Cardioprotective Phytochemicals
por: Treviño-Saldaña, Niria, et al.
Publicado: (2017)

Alterations of SIRT1/SIRT3 subcellular distribution in aging undermine cardiometabolic homeostasis during ischemia and reperfusion
por: Zhang, Jingwen, et al.
Publicado: (2023)

Sildenafil Attenuates Hepatocellular Injury after Liver Ischemia Reperfusion in Rats: A Preliminary Study
por: Savvanis, Spyridon, et al.
Publicado: (2014)

Erythropoietin and sildenafil protect against ischemia/reperfusion injury following testicular torsion in adult rats
por: Kostakis, Ioannis D., et al.
Publicado: (2017)

Sirtuins and SIRT6 in Carcinogenesis and in Diet
por: de Céu Teixeira, Maria, et al.
Publicado: (2019)

Cardioprotective effects of Guanxinshutong (GXST) against myocardial ischemia/ reperfusion injury in rats
por: Liang, Zhuo, et al.
Publicado: (2012)

Glycation abolishes the cardioprotective effects of albumin during ex vivo ischemia‐reperfusion
por: Mapanga, Rudo F., et al.
Publicado: (2017)

Indolylmaleimide Derivative IM-17 Shows Cardioprotective Effects in Ischemia-Reperfusion Injury
por: Dodo, Kosuke, et al.
Publicado: (2018)

Cardioprotective effects of sinomenine in myocardial ischemia/reperfusion injury in a rat model
por: Lu, Changhong, et al.
Publicado: (2022)

SIRT1 is Required for Exercise-Induced Beneficial Effects on Myocardial Ischemia/Reperfusion Injury
por: Wang, Dawei, et al.
Publicado: (2021)

Propofol reduces renal ischemia/reperfusion-induced acute lung injury by stimulating sirtuin 1 and inhibiting pyroptosis
por: Liu, Zhaohui, et al.
Publicado: (2020)

Cardioprotection of CAPE-oNO(2) against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-κB pathway in vivo and in vitro
por: Li, Dejuan, et al.
Publicado: (2017)

Electroacupuncture ameliorates cerebral ischemia/reperfusion injury by suppressing autophagy via the SIRT1-FOXO1 signaling pathway
por: Mei, Zhi-Gang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_uieqqit05k0bsa3qknnluo4no7