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Systemic treatment with CAR-engineered T cells against PSCA delays subcutaneous tumor growth and prolongs survival of mice
BACKGROUND: Adoptive transfer of T cells genetically engineered with a chimeric antigen receptor (CAR) has successfully been used to treat both chronic and acute lymphocytic leukemia as well as other hematological cancers. Experimental therapy with CAR-engineered T cells has also shown promising res...
Autores principales: | Hillerdal, Victoria, Ramachandran, Mohanraj, Leja, Justyna, Essand, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899402/ https://www.ncbi.nlm.nih.gov/pubmed/24438073 http://dx.doi.org/10.1186/1471-2407-14-30 |
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