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Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice
Brain aging is characterized by global changes which are thought to underlie age-related cognitive decline. These include variations in brain activity and the progressive increase in the concentration of soluble amyloid-β (Aβ) oligomers, directly impairing synaptic function and plasticity even in th...
Autores principales: | Mainardi, Marco, Di Garbo, Angelo, Caleo, Matteo, Berardi, Nicoletta, Sale, Alessandro, Maffei, Lamberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899529/ https://www.ncbi.nlm.nih.gov/pubmed/24478697 http://dx.doi.org/10.3389/fnagi.2014.00001 |
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